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Submission Process

During open submission periods, program developers and other interested parties can submit interventions for potential review and inclusion on the NREPP website. This page provides information about minimum requirements for review, ineligible interventions, and where to find more information about the open submission process and minimum requirements.

Minimum Requirements

To be considered for review, interventions must meet the following four minimum requirements. Applicants should be aware that meeting these criteria is necessary but not sufficient to ensure their program is eligible for review.

  1. Outcomes and Populations. For a program to be eligible for review, it must assess a substance use or mental health outcome OR assess a behavioral health outcome of an intervention that targets a mental health or substance-using population. An outcome is the observed characteristic of the target population that an intervention is expected to change. For a list of eligible outcomes, please see the NREPP Outcomes Taxonomy.
  2. Study Designs. A study design describes how the experimental and control groups are formed. To be eligible for NREPP, an intervention must have been evaluated with at least one study that is conducted using an experimental or quasi-experimental design. An experimental design requires that individuals or clusters (e.g., clinics) be randomly assigned to two or more groups. Similarly, a quasi-experimental design compares two or more groups but lacks the random assignment component to sort the units into groups. For NREPP, quasi-experimental designs are required to collect and report (at a minimum) baseline and posttest data for the originally assigned groups. Studies utilizing single-group, time series, or regression discontinuity designs are ineligible at this time, but will be considered under the emerging programs and practices section of the NREPP Learning Center.
  3. Study Comparisons. Study comparisons refer to the comparison between intervention and control/comparison group(s). To rate the impact of a program, NREPP seeks comparisons that allow us to approximate the absolute effect of an intervention. Therefore, to be eligible for NREPP, a study must compare the intervention to an inactive control/comparison. Inactive comparisons include the following: no-treatment, wait-list group, treatment-as-usual, or an intervention that is presumed to be ineffective or substantially less effective than the intervention. In contrast, NREPP does not review active comparisons, where the comparison is expected to yield a relative effect. Active comparisons include comparison/control groups that receive an intervention expected to cause some change (e.g., an intervention rated as promising or effective on an evidence-based registry).

    Other ineligible comparisons include those that compare (1) the effects of the same intervention on various subgroups (e.g., boys vs. girls) or subsets (e.g., pregnant women who are only part of the originally assigned sample) or (2) various (nonzero) doses or components of the same intervention.
  4. Publication Quality. The results of these studies must be published in a peer-reviewed journal or professional publication, or documented in a comprehensive evaluation report, published in 1995 or after. Comprehensive evaluation reports must include, at a minimum, an introduction, a description of research methods (including information about study design, measures, and analysis plan), results (including test statistics), and discussion. Applicants are required to provide full-text documents at the time of submission that demonstrate the intervention meets these minimum requirements. Other research articles, published or unpublished evaluation reports, grant final reports, and replication studies may be submitted as additional supporting documentation. Note: Abstracts, posters, or links to partial articles are regarded as incomplete and will not be considered.
Applicants are required to provide full-text documents at the time of submission that demonstrate the intervention meets these minimum requirements. Other research articles, published or unpublished evaluation reports, grant final reports, and replication studies may be submitted as additional supporting documentation. Note: Abstracts or links to partial articles are regarded as incomplete and will not be considered.

Ineligible Interventions

The following types of interventions are not eligible for review:

  • Stand-alone pharmacologic treatments are not eligible for review and should not be submitted to NREPP. The evidence base for pharmacologic treatments is reviewed and approved by the U.S. Food and Drug Administration (FDA). FDA–approved pharmacotherapy interventions (on-label use) are considered for NREPP review only when combined with one or more behavioral or psychosocial treatment(s).
  • Interventions that have been developed or evaluated with funds or other support, either partially or wholly, from organizations whose goals or activities are determined to be inconsistent with SAMHSA’s mission.
Applicants are required to provide full-text documents at the time of submission that demonstrate the intervention meets these minimum requirements. Other research articles, published or unpublished evaluation reports, grant final reports, and replication studies may be submitted as additional supporting documentation. Note: Abstracts or links to partial articles are regarded as incomplete and will not be considered.

For More Information

To submit questions or comments about the open submission process or minimum requirements for review, please contact us by email at nrepp@samhsa.hhs.gov, by phone at 1-866-43NREPP (1-866-436-7377), or through the online contact form.

Announcements About Future Open Submission Periods

All open submission periods will be announced on the NREPP website. If you wish to receive emailed announcements about future open submission periods, please join our mailing list.

Revised 9/26/17