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The NREPP Open Submission Process

Welcome to the new NREPP Open Submission process! Open submission period begins on November 23, 2015 and closes on January 26, 2016.

Minimum Requirements

It is extremely important that you become familiar with the minimum requirements for submission. To be considered for review, interventions must meet the following three minimum requirements:

  • Research or evaluation of the intervention has assessed mental health or substance use outcomes among individuals, communities, or populations OR other behavioral health related outcomes on individuals, communities, or populations with or at risk of mental health issues or substance use problems.
  • Evidence of these outcomes has been demonstrated in at least one study using an experimental or quasi-experimental design. Experimental designs require random assignment, a control or comparison group, and pre- and post-intervention outcome assessments. Quasi-experimental designs do not require random assignment, but do require a comparison or control group and pre- and post-intervention outcome assessments. Comparison/control groups must be a no-treatment control group, a wait-list control group, a treatment-as-usual comparison group, or an intervention that is presumed to be ineffective or substantially less effective than the intervention (e.g., a ‘‘placebo’’ control or, in cases in which providing no treatment might be considered unethical, less effective treatments, even if not treatment-as-usual, such as ‘‘supportive therapy’’). Studies with single-group, pretest-posttest designs or single-group, longitudinal/multiple time series do not meet this requirement, but will be considered to identify emerging programs and practices for consideration in the Learning Center.

    Comparative effectiveness trials, in which two interventions, both presumed to be equally effective, are compared, and studies in which the effects of the same intervention on various subpopulations are compared or in which various doses or components of the same intervention are compared will not be reviewed, but may be submitted as supporting documentation.
  • The results of these studies have been published in a peer-reviewed journal or other professional publication, or documented in a comprehensive evaluation report, published within the previous 25 years (1990 or later). Comprehensive evaluation reports must include a review of the literature, theoretical framework, purpose, methodology, findings/results with statistical analysis and p values for significant outcomes, discussion, and conclusions.

Additional Information

Applicants are required to provide full-text documents at the time of submission that demonstrate the intervention meets these minimum requirements. Other research articles, published or unpublished evaluation reports, grant final reports, and replication studies may be submitted as additional supporting documentation.

Abstracts or links to partial articles are regarded as incomplete and will not be considered. NREPP will no longer require programs and practices to have developed implementation materials, training and support resources, and quality assurance procedures. However, programs and practices with such dissemination and/or implementation resources will be considered for prioritized review if within the priorities established by the SAMHSA review process, and the materials, along with the location of their availability, will be listed in the program or practice profile.

If you are submitting more than one program, you will need to submit information about one program at a time.


To submit an intervention, you must first create an account. Your account will allow you to initiate an application and save your work until you complete the submission. Once you have an account, you can log in to view the status of your submission.

Registration for open submission will become available on November 23, 2015.

For more information on preparing a submission and to learn more about the changes to the NREPP review process, see the July 7, 2015 Federal Register notice and see the revised content on the Reviews and Submissions pages